A big yes
Assembled for a gaming configuration in a Be quiet Pure Base 500DX case with a Ryzen 9 7900X3D and 2 G.Skill Flare X5 Low Profile DDR5 6Ghz memory modules (2x16 GB) plus a 4060 graphics card.
No problem, everything was recognised without a BIOS update.
It's well equipped in terms of connectors and there are quality heat sinks everywhere, including the 3 M2 slots, one of which is PCI 5.0. The graphics card slot is PCI Express 4.0. I hesitated, but current cards (consumer/gamer range) don't saturate this bus, so it's not a problem. Booting Windows 11 is ultra-fast, taking less than 2 seconds past the boot screen. The Samsung pro 2TB SSD should help.
Be careful with the processor socket, you need to read the instructions carefully when installing the CPU to avoid exposing the motherboard pins, as they are very thin and fragile.